The sample size calculation was based on a presumed odds ratio

admin on 19 de Novembro de 2012

The time to develop arm lymphoedema was comparable between the two group during the first year after surgery (hazard ratio 1.3, 0.6 to 2.5; P=0.49). The sample size calculation was based on a presumed odds ratio of 0.3, which is not included in the 95% confidence interval. This odds ratio was calculated as (presumed cumulative incidence of lymphoedema in intervention group/presumed cumulative incidence of no lymphoedema in intervention group)(presumed cumulative incidence of no lymphoedema in control group/presumed cumulative incidence of lymphoedema in control group) or (10/90)(70/30).Conclusion Manual lymph drainage in addition to guidelines and exercise therapy after axillary lymph node dissection for breast cancer is unlikely to have a medium to large effect in reducing the incidence of arm lymphoedema in the short term.Trial registration Netherlands Trial Register No NTR 1055.IntroductionWorldwide, breast cancer is the most common cancer in women.

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pandora jewelry The importance of the assumptions for t methods diminishes as sample size increases.Alternative methods, such as the sign test, MannWhitney test, and rank correlation , do not require the data to follow a particular distribution. They work by using the rank order of observations rather than the measurements themselves. Methods which do not require us to make distributional assumptions about the data, such as the rank methods, are called non parametric methods. pandora jewelry

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